Dorsolateral Prefrontal Cortex : A Possible Target for Modulating Dyskinesias in Parkinson's Disease by Repetitive Transcranial Magnetic Stimulation
Identifieur interne : 002406 ( Main/Exploration ); précédent : 002405; suivant : 002407Dorsolateral Prefrontal Cortex : A Possible Target for Modulating Dyskinesias in Parkinson's Disease by Repetitive Transcranial Magnetic Stimulation
Auteurs : I. Rektorova [République tchèque] ; S. Sedlackova [République tchèque] ; S. Telecka [République tchèque] ; A. Hlubocky [République tchèque] ; I. Rektor [République tchèque]Source :
- International Journal of Biomedical Imaging : (Print) [ 1687-4188 ] ; 2008.
Descripteurs français
- Pascal (Inist)
English descriptors
Abstract
We studied whether five sessions of 10 Hz repetitive transcranial magnetic stimulation (rTMS treatment) applied over the dorsolateral prefrontal cortex (DLPFC) or the primary motor cortex (MC) in advanced Parkinson's disease (PD) patients would have any effect on L-dopa-induced dyskinesias and cortical excitability. We aimed at a randomised, controlled study. Single-pulse transcranial magnetic stimulation (TMS), paired-pulse transcranial magnetic stimulation, and the Unified Parkinson's Disease Rating Scale (UPDRS parts III and IV) were performed prior to, immediately after, and one week after an appropriate rTMS treatment. Stimulatìon of the left DLPFC induced a significant motor cortex depression and a trend towards the improvement of L-dopa-induced dyskinesias.
Affiliations:
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Sedlackova</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>First Department of Neurology, Masaryk University, Saint Anne's Hospital, Pekařská 53</s1><s2>65691 Brno</s2><s3>CZE</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>République tchèque</country><placeName><settlement type="city">Brno</settlement><region>Moravie</region></placeName></affiliation></author><author><name sortKey="Telecka, S" sort="Telecka, S" uniqKey="Telecka S" first="S." last="Telecka">S. 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Imaging : (Print)</title><idno type="ISSN">1687-4188</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Biomedical engineering</term><term>Depression</term><term>Dyskinesia</term><term>Parkinson disease</term><term>Stimulation</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Dyskinésie</term><term>Maladie de Parkinson</term><term>Etat dépressif</term><term>Stimulation</term><term>Génie biomédical</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We studied whether five sessions of 10 Hz repetitive transcranial magnetic stimulation (rTMS treatment) applied over the dorsolateral prefrontal cortex (DLPFC) or the primary motor cortex (MC) in advanced Parkinson's disease (PD) patients would have any effect on L-dopa-induced dyskinesias and cortical excitability. We aimed at a randomised, controlled study. Single-pulse transcranial magnetic stimulation (TMS), paired-pulse transcranial magnetic stimulation, and the Unified Parkinson's Disease Rating Scale (UPDRS parts III and IV) were performed prior to, immediately after, and one week after an appropriate rTMS treatment. Stimulatìon of the left DLPFC induced a significant motor cortex depression and a trend towards the improvement of L-dopa-induced dyskinesias.</div></front></TEI><affiliations><list><country><li>République tchèque</li></country><region><li>Moravie</li></region><settlement><li>Brno</li></settlement></list><tree><country name="République tchèque"><region name="Moravie"><name sortKey="Rektorova, I" sort="Rektorova, I" uniqKey="Rektorova I" first="I." last="Rektorova">I. Rektorova</name></region><name sortKey="Hlubocky, A" sort="Hlubocky, A" uniqKey="Hlubocky A" first="A." last="Hlubocky">A. Hlubocky</name><name sortKey="Rektor, I" sort="Rektor, I" uniqKey="Rektor I" first="I." last="Rektor">I. Rektor</name><name sortKey="Sedlackova, S" sort="Sedlackova, S" uniqKey="Sedlackova S" first="S." last="Sedlackova">S. Sedlackova</name><name sortKey="Telecka, S" sort="Telecka, S" uniqKey="Telecka S" first="S." last="Telecka">S. Telecka</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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